Estudio fitoquimico y actividad antimicrobiana de las especies Swinglea glutinosa y Ruta graveolens pertenecientes a la familia rutacea
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Sierra Acevedo, Jorge iván | 2012-09-16
The fractionation of extracts of species Swinglea glutinosa y Ruta graveolens were
characterized to determine their composition photochemistry, for it extracts were
evaluated hexane, dichloromethane, butanol, ethyl acetate and ethanol. Likewise,
the compositions were evaluated in both species essential oil in a yield of 5 and
0,09 % respectively. Metabolites were identified responsible for antimicrobial
activity, corresponding to the hexane extract of Swinglea glutinosa, resulting in the
isolation of two coumarins and dichloromethane extract of Ruta graveolens,
obtaining an alkaloid. Molecular connectivity and structures of the isolated
compounds were defined by analysis of the experiments of 1H, 13C, COSY,
HMBC and NOESY.
Analysis was performed bioactivity against the Artemia salina species fractionation
using extracts of the species S. glutinosa and R. graveolens, the data were
analyzed by probit quantal statistics on study time intervals of 24 hours and 30
minutes respectively, these work intervals was chosen for the reason that, from this
time is generated against crustacean bioactive effect of study . The study was used
aleloquímico against Lactuca sativa seeds, using the statistics of one-way ANOVA
and Dunnet statistical. The results of bioactivity and effect aleloquímico allowed
two coumarins insulator in the species S. glutinosa and an alkaloid in the species
R. graveolens.
LEER